Due to health issues, my partner seriously needed to give up smoking. Dr recommended Champix. After the second week, noticeable changes were deeper depression, more anxiety, smelt worse than a stale smelly ash tray, smelt like rottin meat. As each week passed by he became more aggressive and I could not communicate with him anymore. He took everything I said, out of content and focused on the negative. In the 5th week, spiralling mentally, he tried to commit suicide by cutting his wrists. Fortunately, he text to stay Goodbye and Emergency Services broke down his front door to find him bleeding in the shower. He spent the night in hospital in a locked cell. He is off them but I have lost confidence in our relationship so we have now parted. Previously, I was trying to understanding his depression but with the champix exasibated his disrespectful behaviour we are over. I am now in mental repair mode myself. Please beware of Champix. 10% people successfully committ suicide. This figure is too high especially for already depressed people.